Cliniface started to serve the needs of people living with rare diseases. Collectively 6-8% of people are estimated to be living with a rare disease. Diagnosis, treatment and clinical trials for people living with rare diseases can be extremely challenging. For instance, thirty per cent of rare diseases patients will be referred to an average of six specialists and can wait years or decades to receive a diagnosis. As subtle facial variations may provide critical clues for diagnosis, treatment monitoring and clinical trials, the need for a common interoperable digital tool that provides an objective means of measuring, analysing, determining and sharing facial variations, and that also supports existing and future research has become paramount.